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Imagine what it would feel like to have the perfect skin you’ve always wanted…
Imagine the ease of wearing less makeup or not being afraid to spend your summers in bare skin…
Imagine feeling fully confident in any situation…
The Lumi+ Hydrogen Mister is the new skincare device that uses the power of hydrogen water to rapidly increase skin health and quality.
The mister infuses the water with hydrogen molecules that act as powerful antioxidants. These powerful antioxidants reverse skin issues by reducing free radicals and inflammation.
Scientists have found that free radicals are the main cause of skin damage, aging skin, dryness, wrinkles, and even pimples.
Free radicals are caused by pollution, toxins in food, chemicals, sun exposure, and stress. These free radicals damage our skin cells and decrease overall skin health and quality.
The Lumi+ hydrogen mister supplies the skin with powerful antioxidants. It does so by adding hydrogen molecules to water. These molecules produce rapid skin healing effects by eliminating free radicals and inflammation. This in turn causes your skin to look vibrant and youthful again.
I used to have a lot of problems with my skin. I was starting to see more and more wrinkles and it just didn’t look healthy anymore. Now that I use the Lumi+ Hydrogen Mister, I have got back my youthful glow again! I feel so happy.
- Tamara, 52
I was feeling less good about how my skin started to look. I didn’t understand what was causing it because I eat healthy and take care of my skin. I started using the Lumi+ hydrogen mister and I was amazed by the results. Hydrogen water really makes my skin look younger, more vibrant, and healthy.
- Jennifer, 32
The hydrogen molecules from the Lumi+ cause an upregulation of collagen production in the body. Collagen improves skin elasticity, reduces visible wrinkles, and increases blood flow to the skin. It’s the body’s own protein that’s the secret to optimal skin health and beauty.
$199 Now Only $127 each
Total $254 $234
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*International Shipping +$29.90*
ORDER NOW
$199 Now Only $117 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$29.90*
ORDER NOW*Only Expedited Shipping option available for customers at Rest of World to maintain efficient delivery for our international customers during the pandemic COVID-19
$199 Now Only $127 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$39.90*
ORDER NOW$199 Now Only $117 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$39.90*
ORDER NOW*Only Expedited Shipping option available for customers at Rest of World to maintain efficient delivery for our international customers during the pandemic COVID-19
Hydrogen water contains strong anti-inflammatory properties that eliminate toxins and bacteria in the skin. This causes acne, pimples and blackheads to vanish and restores the smooth surface of the skin.
The Lumi+ Hydrogen Mister is a lightweight and portable device. This means you can easily take it with you wherever you go. Just put it in your bag and take it out whenever you feel like your skin could use some extra vitality.
See our Hydrogen bottle in action - The ONLY hydrogen bottle you will ever need! Here’s what some influencers had to say about it:
21.742 Happy Customers Went Before You
I was on this date and the guy I was with mentioned something about my skin looking unhealthy. I was devastated. Thank god I found the Lumi+ hydrogen mister. It has made my skin so healthy again and I look great! People say I look much younger and vibrant.
- Nathalie, 37
The Lumi+ Hydrogen Mister has done wonders for my skin. I have tried a lot of other products on the market but they didn’t give the results I was looking for. The hydrogen mister has visibel results in - Mary, 61
You are covered by our 100% money-back guarantee. If you’re somehow unhappy with your purchase you can let us know and we’ll give you your money back, no questions asked.
You can now place your order by pressing the button below and entering your details. We’ll make sure to ship the Lumi+ to you as fast as possible.
The over 700 scientific studies (1) undoubtedly show that hydrogen is a powerful weapon
against diseases like:
Hydrogen has also been shown to increase energy, lessen fatigue, improve the immune system, reduce fat cells, increase brain function, reduce wrinkles, increase youthfulness, speed up recovery time and so many more things.
Part of the secret of hydrogen is that it’s such a tiny molecule. Because of its small size it can literally reach anywhere in the body and neutralize the free radicals that are causing the inflammation.
You see hydrogen is a natural gas, and is therefore hard to ingest.
To solve that issue it has to be added to water to create Hydrogen Water. When this is done it can make any simple glass of water into a miraculous health potion.
$199 Now Only $127 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$39.90*
ORDER NOW$199 Now Only $117 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$39.90*
ORDER NOW*Only Expedited Shipping option available for customers at Rest of World to maintain efficient delivery for our international customers during the pandemic COVID-19
Imagine being free from any health problems and diseases for good and living a life of optimal health…
In a moment I will share how to start activating your innate healing abilities by using hydrogen water to become more healthy and resolve any health issues or diseases you might be struggling with.
I’ll show you why taking hydrogen water is the best way to lower the deadly inflammation that causes chronic disease…
And then the stomach aches started. It was so bad I would wake up in the night.
I thought it would just all pass but it didn’t. I tried to pretend that I was okay but deep down inside I knew something was wrong…
I never was that interested in diet or eating healthy. Just not my cup of tea. I was healthy anyway.
My mother was into natural healing herbs and living healthy but I didn’t really care.
After talking to my mother about my health problems she convinced me to at least go to the doctor.
I did and that’s when it all came crashing down.
The doctors at the Milwaukee hospital were nice and good people.
The moment they revealed the shocking truth was devastating. Colon cancer.
They told me I only had one year to live…
But I didn’t want to believe what the doctor said to me…
I was determined to find out how I could heal myself. Even though they told me I didn’t have long to live, I believed deep down that there must be a way.
Chemo and radiation therapy sounded like a slow ticket to a horrible death. Not for me. And my mother agreed.
We started trying all kinds of healing modalities from healing herbs to Reiki, different diets, supplements, juice cleanses, fasting, and many more.
Some things seemed to have a slight effect but the terrible stomach aches continued. Some nights were so horrible I thought I would die then and there.
But then things took an unexpected turn…
It was always my big dream to go there. Something about that country and the people fascinated me.
I wasn’t leaving this world without ever visiting. So I bought a ticket with my savings and off I was.
Somehow my “gut feeling” was that I could maybe find something in Japan that could help me.
I landed in Tokyo and was amazed. Such a busy city and such an interesting culture.
It really gave me such a sense of freedom. I almost forgot that I was sick sometimes. But the stomach pains were an unfriendly reminder that things weren’t good.
After 2 days of sightseeing, I started to feel anxious. Am I wasting my time here? I mean I should focus on my health, right?
I thought maybe I do need to take the chemo and radiation therapy. I mean all this natural healing stuff hasn’t helped so far.
I felt hopeless.
One day I decided to go for a walk in the city. Just to clear my head and to get some clarity around what I had to do.
After almost an hour of walking, I felt that my legs were tired. I had to sit down somewhere.
The problem was that almost everything was closed. It was already later in the evening.
I entered the bar and there were already people there. It was rather quiet and there was a ZEN-like feeling to this bar. Not just an ordinary bar but a place where people could relax.
I ordered a glass of water and sat down on one of the bar stools. I was the only person drinking water in the whole place it seemed.
After being there for 10 minutes, thinking constantly about my condition, I suddenly heard a voice: “Do you mind if I sit next to you? It’s my standard spot”.
I started talking with the man and told him everything about my health struggles.
I told this man everything. He just listened. It felt so liberating to share my story with this stranger in this dusty old Japanese bar.
After talking for a while the man introduced himself and said: “My name is Dr. Kobayashi and thank you for sharing about your battle with cancer. I’m actually a scientist and I’m currently studying the healing effects of a specific type of water.”
“My team and I have done experiments where we combined water with hydrogen and studied the healing effects it can have on the body. Our test results have been amazing so far. We’ve found that it does wonder for lowering inflammation and reversing disease in the body.”
I was all ears after this. The healing effect of Hydrogen water? I’ve never heard about this, my doctors never mentioned that this even exists.
“If you want, you can come over tomorrow to the lab and try out some of the hydrogen water. There’s still one spot left for our experiment tomorrow. ”
“Uhh YES! I will come over tomorrow… I replied.”
“Okay meet me at 1 PM at my lab. Here’s the address” said Dr. Kobayashi, while he handed me a small piece of paper with the address.
You can imagine what happened next… I could barely sleep that night. I was so excited. Could this help me? I felt a sense of hope. The stomach aches were painful but I had some kind of hope.
So the next day I show up at Dr. Kobayashi’s lab. I was 30 minutes early just to make sure I didn’t miss this opportunity
Dr. Kobayashi invited me in and took me to the back of his lab.
There was a big enormous machine there. It looked like something from a star trek movie.
“This is our very own hydrogen water machine. It is called Anoroma. Anoroma makes high-quality hydrogen water from normal tap water.” said Dr. Kobayashi.
He explained that it took years to develop this device. In total it cost him and his team $32.000 to create it.
Dr. Kobayashi switched on the device and it started making loud sounds. It was quite impressive to see. He then asked me to grab a glass from the cupboard. I got the glass and handed it to him. He put the glass in the machine and the machine poured it full of water.
“Here drink this.” Dr. Kobayashi said…
I grabbed the glass and took a sip of the water.
And then another zip.
And another…
Before I knew it I was chucking down the entire glass of water.
My body loved this. I felt it. Is this something special?
I wasn’t sure but my body seemed to know already. It felt good.
And over the next 30 minutes, the good feelings increased. I just felt good.
What I now know about hydrogen water is that it gives energy to the mitochondria of the cells.
These are the powerhouses of the cells. When they function well, you feel vibrant and healthy.
Feeling that immediate positive response was my body getting more energy. It was absorbing the hydrogen water and producing more energy.
This is typically what people see when they drink the water for a while. My response was immediate. It can happen but for most it takes a couple of days.
After about 2-4 weeks people usually feel an increase in positive emotions and general well-being.
The biggest reason why hydrogen water is so effective is because it lowers inflammation by reducing the number of free radicals. Like I mentioned earlier this is absolutely essential for good health.
Hydrogen provided powerful antioxidants and it allows the body to get back into a state where it can naturally heal itself.
Once the body isn’t taxed by all this chronic inflammation it can do what it’s supposed to do and bring back all its cells to their optimal state of health.
Hydrogen water is also one of the best things you can do for your immune system. It helps to fight off viruses and bacteria.
It’s crazy how I now never even get a cold anymore.
I’ve seen this water have stunning effects on people who got sick with the flu. Most of them recovered within a few days of drinking it.
I can’t openly discuss say what effect it could have on the virus that’s currently got the world in its grip. But let’s just say that I’ve got my theories…
I didn’t know about all these things when I just drank hydrogen water for the first time.
Back then everything was still new to me.
The first time we sold the new Lumi+ we sold out within 10 days. We couldn’t keep up with the demand.
This is our second time offering this water bottle to the public. It’s strictly first come and first serve.
We’re not sure how long the supply will last and we have lots of orders coming in daily.
So make sure to act fast if you want to get your hands on a Lumi+.
1 Bottle
Save - $170 + free hydrogen PDF
$399 Now Only $229 each
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Save - $364 + free hydrogen PDF
$399 Now Only $217 each
Total $798 $434
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ORDER NOWThis is a special offer and we don’t know how long we can keep it at this low and cheap price.
Think about it.
The device of Dr. Kobayashi had a price tag of $32.000. Compared to that the Lumi+ is a steal.
It’s also true that most people use the Lumi+ every day of the year.
This means you can get vibrant health and healing of chronic disease for just $0,62 per day.
Are your health and the health of your loved ones worth $0,62 per day?
Most people we talk to believe that this is a no-brainer
And it doesn’t stop there. We even give you a full money-back guarantee:
After drinking the hydrogen for the first time, Dr. Kobayashi asked me to join a longer experiment. This time I got to drink hydrogen water every day for a couple of months.
It just felt good. I wasn’t sure if it would help me with my health problems.
But somehow the stomach aches became less. I first thought it could just be because I was relaxing my mind and body. I mean could this water be that powerful? I wasn’t sure.
One day I decided to get a check at an English-speaking hospital in downtown Tokyo. And there the doctors said something that COMPLETELY blew me away…
“We’re not sure if you’re playing a game with us. It’s not appropriate to take up all this time of the medical staff” one doctor said.
What do you mean? I said. I came here to see how my colon cancer is developing. I feel good but I am still very worried.
“Well sir, we don’t know what colon cancer you’re referring to. Your colon looks perfectly healthy.”
What… Wait… What did you say?”
“You are healthy sir. If you were having issues with your colon, you must have done something to heal. Keep doing whatever you are doing.”
I burst out in tears right then and there.
All this time I was trying to keep things together but this was just too much.
It took me some time to let everything sink in. This truly was a miracle!
After spending a couple more weeks in Tokyo and thanking Dr. Kobayashi about a million times, I felt an urge to go somewhere else.
I looked online and came across this cruise on the Caribbean.
I was healed and I felt so energized and youthful again so I was excited to see more places.
While on the cruise, I met a woman in one of the bars. She told me her name was Nathalie. After talking for a while, she mentioned that she was struggling with an autoimmune disease called Multiple Sclerosis.
It sounded like an awful disease to have. I felt really sorry for her and decided to share about my own struggles with cancer and how I miraculously recovered from my terminal cancer diagnosis.
She was amazed by my story and I could sense that she was curious about Hydrogen water.
I asked her if she wanted to try out the hydrogen water for herself. She said she’d definitely like to try it. I gave her a bottle and we parted ways.
The next day I started walking and met Nathalie again. She was standing on the deck next to the swimming pool.
“I drank the hydrogen water and it felt really good. I was reading all about it and it’s so fascinating.” Nathalie said.
Once the cruise ended, Nathalie and I kept seeing each other and started dating. A few months later she convinced me to go back to Tokyo and see Dr. Kobayashi.
Once back in Tokyo, Dr. Kobayashi was happy to see us and gave us some more of the hydrogen water.
Nathalie’s autoimmune disease eventually went into remission after drinking hydrogen water every day for a couple of weeks.
We both wanted to keep drinking the hydrogen water every day. The problem was we couldn’t take a lot of bottles with us on the plane back. We had to think of something… but what?
I could move to Tokyo and live here for the rest of my life. This
would give me direct access to the hydrogen water of Dr. Kobayashi.
I could try to save up $32,000 to buy all the parts of the big Anoroma
machine and try to build one myself.
Or I could try to create a new and cheaper way to create hydrogen
water. Something that I could easily use anywhere I was.
At that moment, it dawned on me. I have a background in engineering. If I could make machines for a beer factory, I might just be able to create a better hydrogen machine.
I mentioned this to Dr. Kobayashi and Nathalie. I did know that Nathalie had a background in product design. She immediately said she really liked the idea.
Dr. Kobayashi was also enthusiastic about this new idea and after a long conversation, we decided to work together on creating a new type of hydrogen machine.
We tried to make a new portable machine to produce hydrogen cheaply. It was an unbelievable struggle and it took us a couple of years to come up with a working prototype.
I’ll spare you all the details but It was difficult to say the least.
Our first prototype failed the final tests… It was just not portable and effective enough to use.
But then Dr. Kobayashi and his team added a special type of technology called SPE/PEM and it suddenly worked.
We did it!
We didn’t want to keep this new invention just to ourselves. After testing it for about a year we decided it was time to share our creation with the public.
Yes the Lumi+ Hydrogen Mister can be used on all skin types. Hydrogen water has been shown to be healing for all types of skin.
Please use only filtered or normal drinking water/mineral water. Do not use tap/ unfiltered or alkaline water.
Yes, the Lumi+ has been thoroughly tested for safety and efficacy. It has been used by thousands of happy customers now with excellent results.
Yes, your purchase of the Lumi+ is backed by a 30-day guarantee. If you somehow decide
the product is not for you after ordering then we’ll refund your money, no questions asked.
For more information on how to return the Lumi+, please visit our Warranty &
Returns policy page. https://lumiplus.com/pages/warranty-returns-policy.
Yes, we do offer a 1-year defect warranty. If you have any issue with your LUmi+ hydrogen bottle, contact us at: contact@lumiplus.com
Your order will be shipped out from our warehouse within 1-2 business days after receiving your payment. An email confirmation sent when your order has been shipped out. The shipment reaches your doorstep in the stipulated timeline below. We try to keep the delivery times as fast as possible but due to COVID restrictions, there could be a slight delay (1-2 weeks).
USA and Canada :
Rest of World:
* Only Expedited Shipping option available for customers at Rest of World to maintain efficient delivery for our international customers d uring the pandemic COVID-19. * Kindly note that Expedited Shipping does not include custom duties. Please check with your local custom office for those charges.
Not applicable for domestic order within USA.
Every country's customs regulations are different and International orders are subject to duties, customs, and value-added taxes which are not reflected in our prices. The recipient will be responsible for paying these charges upon receipt of your order. Please check with your local customs office for those charges. Some countries may be assessed an additional handling fee for brokering these payments prior to delivery within that country. Lumi+ is not responsible for any customs, duties or import fees (GST/VAT) associated with receiving your order. In the event that the customs duties are not paid for and the goods are shipped back, any return shipping fees will be the responsibility of the recipient.
$199 Now Only $127 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$39.90*
ORDER NOW$199 Now Only $117 each
Total $254 $234
Free USA and Canada Standard Shipping
*International Shipping +$39.90*
ORDER NOW*Only Expedited Shipping option available for customers at Rest of World to maintain efficient delivery for our international customers during the pandemic COVID-19
Royal Society of Chemistry. Chemistry in Its Element - Hydrogen. [ http://www.rsc.org/chemistryworld/podcast/Interactive_Periodic_Table_Transcripts/Hydrogen.asp]
Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. 2007;13:688–694. doi: 10.1038/nm1577. [PubMed] [CrossRef] [Google Scholar]
Pilcher JE. Senn on the Diagnosis of Gastro-Intestinal Perforation by the Rectal Insufflation of Hydrogen Gas. Ann Surg. 1888;8:190–204. [PMC free article] [PubMed] [Google Scholar]
Huang CS, Kawamura T, Toyoda Y, Nakao A. Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res. 2010;44:971–982. doi: 10.3109/10715762.2010.500328. [PubMed] [CrossRef] [Google Scholar]
Liu W, Khatibi N, Sridharan A, Zhang JH. Application of medical gases in the field of neurobiology. Med Gas Res. 2011;1:13. doi:10.1186/2045-9912-1-13. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Hazardous Substances Data Bank. Hazardous Substances Data Bank. [ http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB]
Szarka LA, Camilleri M. Methods for the assessment of small-bowel and colonic transit. Semin Nucl Med. 2012;42:113–123. doi: 10.1053/j.semnuclmed.2011.10.004. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Kayar SR, Axley MJ, Homer LD, Harabin AL. Hydrogen gas is not oxidized by mammalian tissues under hyperbaric conditions. Undersea Hyperb Med. 1994;21:265–275. [PubMed] [Google Scholar]
Dole M, Wilson FR, Fife WP. Hyperbaric hydrogen therapy: a possible treatment for cancer. Science. 1975;190:152–154. doi: 10.1126/science.1166304. [PubMed] [CrossRef] [Google Scholar]
Xie K, Yu Y, Pei Y, Hou L, Chen S, Xiong L, Wang G. Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release. Shock. 2010;34:90–97. [PubMed] [Google Scholar]
Gharib B, Hanna S, Abdallahi OM, Lepidi H, Gardette B, De Reggi M. Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. Compt Rendus Acad Sci III Sci Vie. 2001;324:719–724. [PubMed] [Google Scholar]
Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M. Molecular hydrogen inhibits lipopolysaccharide/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages. Biochem Biophys Res Commun. 2011;411:143–149. doi: 10.1016/j.bbrc.2011.06.116. [PubMed] [CrossRef] [Google Scholar]
Sun Q, Kang Z, Cai J, Liu W, Liu Y, Zhang JH, Denoble PJ, Tao H, Sun X. Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. Exp Biol Med (Maywood) 2009;234:1212–1219. doi: 10.3181/0812-RM-349. [PubMed] [CrossRef] [Google Scholar]
Shi P, Sun W, Shi P. A hypothesis on chemical mechanism of the effect of hydrogen. Med Gas Res. 2012;2:17. doi: 10.1186/2045-9912-2-17. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Qin ZX, Yu P, Qian DH, Song MB, Tan H, Yu Y, Li W, Wang H, Liu J, Wang Q. Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ROS and the TNF-alpha/NF-kappaB pathway. Atherosclerosis. 2012;220:343–350. doi: 10.1016/j.atherosclerosis.2011.11.002. [PubMed] [CrossRef] [Google Scholar]
Chen Y, Jiang J, Miao H, Chen X, Sun X, Li Y. Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. Int J Mol Med. 2013;31:597–606. [PubMed] [Google Scholar]
Wang F, Yu G, Liu SY, Li JB, Wang JF, Bo LL, Qian LR, Sun XJ, Deng XM. Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats. J Surg Res. 2011;167:e339–e344. doi: 10.1016/j.jss.2010.11.005. [PubMed] [CrossRef] [Google Scholar]
Fan M, Xu X, He X, Chen L, Qian L, Liu J, Qing J, Chao Z, Sun X. Protective Effects of Hydrogen-rich Saline against Erectile Dysfunction in a Streptozotocin-Induced Diabetic Rat Model. J Urol. 2012. [PubMed] [CrossRef]
Cai J, Kang Z, Liu K, Liu W, Li R, Zhang JH, Luo X, Sun X. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Res. 2009;1256:129–137. [PubMed] [Google Scholar]
Hugyecz M, Mracsko E, Hertelendy P, Farkas E, Domoki F, Bari F. Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. Brain Res. 2011;1404:31–38. [PubMed] [Google Scholar]
Ono H, Nishijima Y, Adachi N, Sakamoto M, Kudo Y, Kaneko K, Nakao A, Imaoka T. A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level. Med Gas Res. 2012;2:21. doi: 10.1186/2045-9912-2-21. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Domoki F, Olah O, Zimmermann A, Nemeth I, Toth-Szuki V, Hugyecz M, Temesvari P, Bari F. Hydrogen is neuroprotective and preserves cerebrovascular reactivity in asphyxiated newborn pigs. Pediatr Res. 2010;68:387–392. [PubMed] [Google Scholar]
Seo T, Kurokawa R, Sato B. A convenient method for determining the concentration of hydrogen in water: use of methylene blue with colloidal platinum. Med Gas Res. 2012;2:1. doi: 10.1186/2045-9912-2-1. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Ostojic SM. The Effects of Hydrogen-rich Formulation for Treatment of Sport-related Soft Tissue Injuries. 2012. Clinical Trials. http://clinicaltrials.gov/ct2/show/NCT01759498.
Hoyert DL, Xu JQ. Deaths: Preliminary data for 2011. National vital statistics reports; vol 61. http://www.cdc.gov/nchs/data/nvsr/nvsr61/nvsr61_06.pdf.[PubMed]
Matsushita T, Kusakabe Y, Kitamura A, Okada S, Murase K. Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging. Magn Reson Med Sci. 2011;10:169–176. doi: 10.2463/mrms.10.169. [PubMed] [CrossRef] [Google Scholar]
Nakayama M, Nakano H, Hamada H, Itami N, Nakazawa R, Ito S. A novel bioactive haemodialysis system using dissolved dihydrogen (H2) produced by water electrolysis: a clinical trial. Nephrol Dial Transplant. 2010;25:3026–3033. doi: 10.1093/ndt/gfq196. [PubMed] [CrossRef] [Google Scholar]
Kitamura A, Kobayashi S, Matsushita T, Fujinawa H, Murase K. Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced CT. Br J Radiol. 2010;83:509–514. doi: 10.1259/bjr/25604811. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Yu P, Wang Z, Sun X, Chen X, Zeng S, Chen L, Li S. Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage. Biochem Biophys Res Commun. 2011;409:350–355. doi: 10.1016/j.bbrc.2011.05.024. [PubMed] [CrossRef] [Google Scholar]
Katakura M, Hashimoto M, Tanabe Y, Shido O. Hydrogen-rich water inhibits glucose and alpha,beta -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney. Med Gas Res. 2012;2:18. doi: 10.1186/2045-9912-2-18. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Wang QJ, Zha XJ, Kang ZM, Xu MJ, Huang Q, Zou DJ. Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress. Chin Med J. 2012;125:1633–1637. [PubMed] [Google Scholar]
Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, Kitawaki J, Imai S, Nakano K, Ohta M. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008;28:137–143. doi: 10.1016/j.nutres.2008.01.008. [PubMed] [CrossRef] [Google Scholar]
Pimentel C, Batista-Nascimento L, Rodrigues-Pousada C, Menezes RA. Oxidative stress in Alzheimer's and Parkinson's diseases: insights from the yeast Saccharomyces cerevisiae. Oxidative Med Cell Longevity. 2012;2012:132146. [PMC free article] [PubMed] [Google Scholar]
Li J, Wang C, Zhang JH, Cai JM, Cao YP, Sun XJ. Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. Brain Res. 2010;1328:152–161. [PubMed] [Google Scholar]
Wang C, Li J, Liu Q, Yang R, Zhang JH, Cao YP, Sun XJ. Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-kappaB activation in a rat model of amyloid-beta-induced Alzheimer's disease. Neurosci Lett. 2011;491:127–132. doi: 10.1016/j.neulet.2011.01.022. [PubMed] [CrossRef] [Google Scholar]
Cai J, Kang Z, Liu WW, Luo X, Qiang S, Zhang JH, Ohta S, Sun X, Xu W, Tao H, Li R. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci Lett. 2008;441:167–172. doi: 10.1016/j.neulet.2008.05.077. [PubMed] [CrossRef] [Google Scholar]
Ji Q, Hui K, Zhang L, Sun X, Li W, Duan M. The effect of hydrogen-rich saline on the brain of rats with transient ischemia. J Surg Res. 2011;168:e95–e101. doi: 10.1016/j.jss.2011.01.057. [PubMed] [CrossRef] [Google Scholar]
Liu Y, Liu W, Sun X, Li R, Sun Q, Cai J, Kang Z, Lv S, Zhang JH, Zhang W. Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model. Med Gas Res. 2011;1:15. doi: 10.1186/2045-9912-1-15. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Sato Y, Kajiyama S, Amano A, Kondo Y, Sasaki T, Handa S, Takahashi R, Fukui M, Hasegawa G, Nakamura N. Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice. Biochem Biophys Res Commun. 2008;375:346–350. doi: 10.1016/j.bbrc.2008.08.020. [PubMed] [CrossRef] [Google Scholar]
Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease. Neurosci Lett. 2009;453:81–85. doi: 10.1016/j.neulet.2009.02.016. [PubMed] [CrossRef] [Google Scholar]
to M, Hirayama M, Yamai K, Goto S, Ito M, Ichihara M, Ohno K. Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson's disease in rats. Med Gas Res. 2012;2:15. doi: 10.1186/2045-9912-2-15. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, Yamaguchi H, Sakumi K, Yamakawa Y, Kido MA, Takaki A. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PLoS One. 2009;4:e7247. doi: 10.1371/journal.pone.0007247. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Yoritaka A, Takanashi M, Hirayama M, Nakahara T, Ohta S, Hattori N. Pilot study of H(2) therapy in Parkinson's disease: A randomized double-blind placebo-controlled trial. Mov Disord. 2013. [PubMed]
Ji X, Liu W, Xie K, Liu W, Qu Y, Chao X, Chen T, Zhou J, Fei Z. Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress. Brain Res. 2010;1354:196–205. [PubMed] [Google Scholar]
Manaenko A, Lekic T, Ma Q, Zhang JH, Tang J. Hydrogen Inhalation Ameliorated Mast Cell-Mediated Brain Injury After Intracerebral Hemorrhage in Mice. Crit Care Med. 2013;41:1266–1275. doi: 10.1097/CCM.0b013e31827711c9. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Matchett GA, Fathali N, Hasegawa Y, Jadhav V, Ostrowski RP, Martin RD, Dorotta IR, Sun X, Zhang JH. Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models. Brain Res. 2009;1259:90–97. [PubMed] [Google Scholar]
Eckermann JM, Krafft PR, Shoemaker L, Lieberson RE, Chang SD, Colohan A. Potential application of hydrogen in traumatic and surgical brain injury, stroke and neonatal hypoxia-ischemia. Med Gas Res. 2012;2:11. doi: 10.1186/2045-9912-2-11. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Mao YF, Zheng XF, Cai JM, You XM, Deng XM, Zhang JH, Jiang L, Sun XJ. Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. Biochem Biophys Res Commun. 2009;381:602–605. doi: 10.1016/j.bbrc.2009.02.105. [PubMed] [CrossRef] [Google Scholar]
Fang Y, Fu XJ, Gu C, Xu P, Wang Y, Yu WR, Sun Q, Sun XJ, Yao M. Hydrogen-rich saline protects against acute lung injury induced by extensive burn in rat model. J Burn Care Res. 2011;32:e82–e91. doi: 10.1097/BCR.0b013e318217f84f. [PubMed] [CrossRef] [Google Scholar]
Sun Q, Cai J, Liu S, Liu Y, Xu W, Tao H, Sun X. Hydrogen-rich saline provides protection against hyperoxic lung injury. J Surg Res. 2011;165:e43–e49. doi: 10.1016/j.jss.2010.09.024. [PubMed] [CrossRef] [Google Scholar]
Wang Y, Jing L, Zhao XM, Han JJ, Xia ZL, Qin SC, Wu YP, Sun XJ. Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. Respir Res. 2011;12:26. doi: 10.1186/1465-9921-12-26. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Shi J, Yao F, Zhong C, Pan X, Yang Y, Lin Q. Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats. Heart Lung Circ. 2012;21:556–563. doi: 10.1016/j.hlc.2012.05.782. [PubMed] [CrossRef] [Google Scholar]
Saitoh Y, Okayasu H, Xiao L, Harata Y, Miwa N. Neutral pH hydrogen-enriched electrolyzed water achieves tumor-preferential clonal growth inhibition over normal cells and tumor invasion inhibition concurrently with intracellular oxidant repression. Oncol Res. 2008;17:247–255. doi: 10.3727/096504008786991620. [PubMed] [CrossRef] [Google Scholar]
Zhao L, Zhou C, Zhang J, Gao F, Li B, Chuai Y, Liu C, Cai J. Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice. Int J Biol Sci. 2011;7:297–300. [PMC free article] [PubMed] [Google Scholar]
Wang J, Yi J. Cancer cell killing via ROS: to increase or decrease, that is the question. Cancer Biol Ther. 2008;7:1875–1884. doi: 10.4161/cbt.7.12.7067. [PubMed] [CrossRef] [Google Scholar]
Qian L, Cao F, Cui J, Wang Y, Huang Y, Chuai Y, Zaho L, Jiang H, Cai J. The potential cardioprotective effects of hydrogen in irradiated mice. J Radiat Res. 2010;51:741–747. doi: 10.1269/jrr.10093. [PubMed] [CrossRef] [Google Scholar]
Zhang Y, Sun Q, He B, Xiao J, Wang Z, Sun X. Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. Int J Cardiol. 2011;148:91–95. doi: 10.1016/j.ijcard.2010.08.058. [PubMed] [CrossRef] [Google Scholar]
Hayashida K, Sano M, Ohsawa I, Shinmura K, Tamaki K, Kimura K, Endo J, Katayama T, Kawamura A, Kohsaka S. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun. 2008;373:30–35. doi: 10.1016/j.bbrc.2008.05.165. [PubMed] [CrossRef] [Google Scholar]
Benfeito S, Oliveira C, Soares P, Fernandes C, Silva T, Teixeira J, Borges F. Antioxidant therapy: Still in search of the ‘magic bullet’ Mitochondrion. 2012. [PubMed]
Rigon A, Sotti G, Zanesco L, Scarzello G, Friso L, Casara D, Cauzzo C, Calzavara F. Meningeal prophylaxis with radiocolloids in childhood leukemia and non-Hodgkin's lymphoma. Radiol Med. 1985;71:517–520. [PubMed] [Google Scholar]
Ni XX, Cai ZY, Fan DF, Liu Y, Zhang RJ, Liu SL, Kang ZM, Liu K, Li RP, Sun XJ, Xu WG. Protective effect of hydrogen-rich saline on decompression sickness in rats. Aviat Space Environ Med. 2011;82:604–609. doi: 10.3357/ASEM.2964.2011. [PubMed] [CrossRef] [Google Scholar]
Hooker SK, Fahlman A, Moore MJ, de Soto NA, de Quiros YB, Brubakk AO, Costa DP, Costidis AM, Dennison S, Falke KJ. Deadly diving? Physiological and behavioural management of decompression stress in diving mammals. Proc Biol Sci. 2012;279:1041–1050. doi: 10.1098/rspb.2011.2088. [PMC free article] [PubMed] [CrossRef] [Google Scholar]